Agonize (over) NYT crossword clue

The answer to the New York Times The Mini crossword clue “Agonize (over)” is FRET. This verb means to feel or express worry, anxiety, or discontent, especially in a persistent or restless way. When someone frets over something, they are mentally agitated or preoccupied with concern, often about things they cannot control.

The clue uses the word “agonize” to suggest deep, emotional turmoil, and the addition of “(over)” points to a common phrasal usage—“fret over.” FRET is the ideal answer here because it precisely captures the sense of ongoing worry or distress implied in the clue while fitting neatly into the crossword format.